Description

2-(Cyclopropylmethoxy)-4-Fluorobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant synthetic utility. Its molecular structure, featuring a cyclopropylmethoxy ether and a formyl group on a fluorinated benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity imparted by the fluorinated aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where the fluorobenzaldehyde moiety modifies electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Cyclopropylmethoxy)-4-Fluorobenzaldehyde
CAS No.	883525-53-9
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	4-Fluoro-2-(cyclopropylmethoxy)benzaldehyde; 2-(Cyclopropylmethoxy)-4-fluorobenzaldehyde; 4-Fluoro-2-(cyclopropoxymethyl)benzaldehyde; Benzaldehyde, 4-fluoro-2-(cyclopropylmethoxy)-; 883525-53-9; 4-Fluoro-2-cyclopropylmethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-(Cyclopropylmethoxy)-4-Fluorobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and scale-up processes. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.