Description

4-(Cyclopropylmethoxy)[1,1'-Biphenyl]-3-Carbaldehyde is a high-purity, functionalized biphenyl derivative characterized by its cyclopropylmethoxy and aldehyde groups. This compound serves as a versatile and critical advanced pharmaceutical intermediate for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Reagent: Used in cross-coupling reactions, such as Suzuki-Miyaura couplings, facilitated by the biphenyl scaffold.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic pathways and creating chemical libraries for screening.
• Ligand & Catalyst Precursor: The aldehyde functionality allows for the creation of chiral ligands or complex molecules used in asymmetric catalysis.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its conjugated biphenyl core.

Basic Information

Product Name	4-(Cyclopropylmethoxy)[1,1'-Biphenyl]-3-Carbaldehyde
CAS No.	883523-34-0
Molecular Formula	C17H16O2
Molecular Weight	252.31 g/mol
Synonyms	4-(Cyclopropylmethoxy)-[1,1'-biphenyl]-3-carboxaldehyde; 3-Formyl-4-(cyclopropylmethoxy)biphenyl; [1,1'-Biphenyl]-3-carboxaldehyde, 4-(cyclopropylmethoxy)-; 4-Cyclopropylmethoxy-3'-formylbiphenyl; Biphenyl-3-carbaldehyde, 4-(cyclopropylmethoxy)-; 4-(Cyclopropylmethoxy)-1,1'-biphenyl-3-carbaldehyde; 3'-Formyl-4-(cyclopropylmethoxy)-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 4-(Cyclopropylmethoxy)[1,1'-Biphenyl]-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.