Description

3-Benzyloxy-5-Fluorobenzaldehyde is a versatile aromatic aldehyde building block featuring both benzyloxy and fluorine substituents. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on new active ingredients. The strategic placement of the fluorine atom and the protected hydroxyl group makes it a critical precursor for constructing molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine moiety can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to create complex biaryl structures.
• Fluorescent Dye & Sensor Development: Acts as a starting material for synthesizing fluorophores and molecular sensors used in bioimaging and diagnostics.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	3-Benzyloxy-5-Fluorobenzaldehyde
CAS No.	883443-39-8
Molecular Formula	C₁₄H₁₁FO₂
Molecular Weight	230.24 g/mol
Synonyms	5-Fluoro-3-(phenylmethoxy)benzaldehyde; 3-(Benzyloxy)-5-fluorobenzaldehyde; Benzaldehyde, 3-(benzyloxy)-5-fluoro-; 5-Fluoro-3-benzyloxybenzaldehyde; 3-Benzyloxy-5-fluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.