Description

Potassium Ethyltrifluoroborate is an organoboron reagent widely used as a stable, air- and moisture-tolerant precursor in cross-coupling reactions. Its primary value lies in enabling efficient Suzuki-Miyaura couplings, a cornerstone methodology for constructing carbon-carbon bonds in complex molecule synthesis. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and scalable boron reagents for fine chemical and active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and alkyl-aryl motifs found in drug candidates.
• Agrochemical Production: Used in the synthesis of complex molecules for crop protection agents, leveraging its stability for scalable manufacturing.
• Ligand and Catalyst Development: Serves as a reagent in the preparation of novel ligands and organometallic catalysts for research and development.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Library Construction: Facilitates the rapid and diverse synthesis of compound libraries for high-throughput screening in drug discovery.
• Process Chemistry & Scale-up: Valued for its handling stability compared to boronic acids, making it suitable for optimizing and scaling coupling reactions.

Basic Information

Product Name	Potassium Ethyltrifluoroborate
CAS No.	882871-21-8
Molecular Formula	C2H5BF3K
Molecular Weight	139.97 g/mol
Synonyms	Potassium Ethyltrifluoroboronate; Ethyltrifluoroborate Potassium Salt; Potassium Ethyl-Trifluoroborane; Ethyl Potassium Trifluoroborate; Ethyl-BF3K; KEtBF3; (Ethyl)Trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium Ethyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥97% (by NMR or titration). Each lot is characterized by NMR spectroscopy (1H, 11B, 13C) and ion chromatography (for halides) to confirm identity and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR/Titration)	≥ 97%
Potassium Content (ICP)	27.0 - 28.5 %
Fluoride Content (IC)	≤ 1.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.