Description

(E)-Ethyl 3-(2,4,5-Trifluorophenyl) Acrylate is a high-purity fluorinated acrylate ester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile, reactive handle for constructing complex molecules with trifluoromethylphenyl motifs, which are critical for modulating physicochemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers with unique optical or surface properties.
• Liquid Crystal & OLED Materials: Incorporated into the molecular design of advanced electronic display components to improve performance.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags or molecular probes for diagnostic and research applications.
• Cross-Coupling Reactions: Acts as a competent substrate in Heck, Suzuki, and other palladium-catalyzed coupling reactions to build complex biaryl systems.

Basic Information

Product Name	(E)-Ethyl 3-(2,4,5-Trifluorophenyl) Acrylate
CAS No.	882856-63-5
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	Ethyl (E)-3-(2,4,5-Trifluorophenyl)acrylate; (E)-Ethyl 3-(2,4,5-Trifluorophenyl)-2-propenoate; 2-Propenoic acid, 3-(2,4,5-trifluorophenyl)-, ethyl ester, (E)-; Ethyl (E)-3-(2,4,5-Trifluorophenyl)propenoate; 882856-63-5; Acrylic acid, 3-(2,4,5-trifluorophenyl)-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and commercial use. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and isomeric composition. Certificates of Analysis (COA) detailing all relevant specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio)	≥ 98:2 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.