Description

1-(4-Fluorophenyl)-3-[(2,3,4,5,6-Pentamethylbenzyl)Sulfanyl]-1-Propanone is a high-value, synthetically tailored organic intermediate featuring a unique fluorinated aromatic and pentamethylbenzylthioether structure. This compound is engineered to serve as a critical building block in advanced pharmaceutical and agrochemical research, offering precise reactivity for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for applications in novel active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides, where the fluorine atom and bulky aromatic group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry for the design of specialized ligands, facilitating catalytic processes in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for developing advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms or protein interactions due to its modifiable ketone and sulfide functionalities.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[(2,3,4,5,6-Pentamethylbenzyl)Sulfanyl]-1-Propanone
CAS No.	882749-16-8
Molecular Formula	C21H23FOS
Molecular Weight	342.47 g/mol
Synonyms	3-[(2,3,4,5,6-Pentamethylbenzyl)thio]-1-(4-fluorophenyl)-1-propanone; 1-Propanone, 1-(4-fluorophenyl)-3-[(2,3,4,5,6-pentamethylbenzyl)thio]-; 4-Fluoro-β-(pentamethylbenzylthio)propiophenone; 882749-16-8; 1-(4-Fluorophenyl)-3-(pentamethylbenzylthio)propan-1-one
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-3-[(2,3,4,5,6-Pentamethylbenzyl)Sulfanyl]-1-Propanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for impurity profiling. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.