Description

1-[1,1'-Biphenyl]-4-Yl-3-[(4-Fluorophenyl)Sulfanyl]-1-Propanone is a high-purity, specialized organic intermediate featuring a biphenyl core linked to a fluorinated thioether ketone moiety. This compound matters for its role as a critical building block in advanced organic synthesis, enabling the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate complex, functionalized aromatic structures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or pesticides where the biphenyl and fluorophenyl groups contribute to biological activity and stability.
• Liquid Crystal & OLED Materials: Acts as a building block for creating advanced organic electronic materials due to its rigid, conjugated biphenyl structure and potential for further functionalization.
• Polymer Science: Employed in the synthesis of specialty polymers and resins, where it can be incorporated to modify thermal stability, refractive index, or other physical properties.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new organic reactions, catalytic processes, and the creation of novel chemical libraries.
• Material Science Additive: Investigated for use as an additive or cross-linking agent in high-performance coatings and composites.

Basic Information

Product Name	1-[1,1'-Biphenyl]-4-Yl-3-[(4-Fluorophenyl)Sulfanyl]-1-Propanone
CAS No.	882749-09-9
Molecular Formula	C21H17FOS
Molecular Weight	336.42 g/mol
Synonyms	3-[(4-Fluorophenyl)thio]-1-(4-phenylphenyl)-1-propanone; 1-(Biphenyl-4-yl)-3-[(4-fluorophenyl)sulfanyl]propan-1-one; 4'-Fluoro-4-(3-oxo-3-(biphenyl-4-yl)propylthio)benzene; [1,1'-Biphenyl]-4-propanone, 1-[1,1'-biphenyl]-4-yl-3-[(4-fluorophenyl)thio]-; Biphenyl-fluorophenyl thioether ketone intermediate
EINECS	Contact for details

Quality Control

Our 1-[1,1'-Biphenyl]-4-Yl-3-[(4-Fluorophenyl)Sulfanyl]-1-Propanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.