Description

1-(4-Bromophenyl)-3-(2,4-Difluoroanilino)-1-Propanone is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise and reliable synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its difluorinated aniline moiety.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for transition metal catalysis and asymmetric synthesis.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Fluorinated Compound Library: An essential component for building diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-(4-Bromophenyl)-3-(2,4-Difluoroanilino)-1-Propanone
CAS No.	882748-48-3
Molecular Formula	C15H12BrF2NO
Molecular Weight	340.17 g/mol
Synonyms	1-Propanone, 1-(4-bromophenyl)-3-[(2,4-difluorophenyl)amino]-; 3-[(2,4-Difluorophenyl)amino]-1-(4-bromophenyl)-1-propanone; N-(2,4-Difluorophenyl)-3-(4-bromobenzoyl)propylamine; 1-(4-Bromobenzoyl)-3-(2,4-difluoroanilino)propane; 882748-48-3; 4'-Bromo-3-(2,4-difluoroanilino)propiophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-3-(2,4-Difluoroanilino)-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.