Description

5-Chloro-2-Fluoropyridine-3-Carboxaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis.

Basic Information

Product Name	5-Chloro-2-Fluoropyridine-3-Carboxaldehyde
CAS No.	882679-90-5
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	3-Formyl-5-chloro-2-fluoropyridine; 5-Chloro-2-fluoro-3-pyridinecarboxaldehyde; 2-Fluoro-5-chloropyridine-3-carbaldehyde; 5-Chloro-2-fluoronicotinaldehyde; 882679-90-5; 5-Chloro-2-fluoro-3-formylpyridine; 3-Pyridinecarboxaldehyde, 5-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoropyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.