Description

4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a valuable boronic ester functional group. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those requiring specific biaryl motifs for target binding.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for organic semiconductors, ligands for catalysts, and monomers for advanced polymers.
• Chemical Synthesis: Enables efficient carbon-carbon bond formation in complex multi-step synthetic routes for fine chemicals.
• Academic & R&D: Employed in university and corporate laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	882679-88-1
Molecular Formula	C14H20BNO3
Molecular Weight	261.13 g/mol
Synonyms	3-Carbamoyl-4-methylphenylboronic acid pinacol ester; 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid amide; 3-Aminocarbonyl-4-methylbenzeneboronic acid pinacol ester; Benzoic acid, 3-(aminocarbonyl)-4-methyl-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl ester; CAS 882679-88-1; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylbenzamide; Pinacol 3-Carbamoyl-4-methylbenzeneboronate
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.