Description

n-(4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropanecarboxamide is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound matters because it serves as a critical building block in modern synthetic chemistry, enabling key carbon-carbon bond-forming reactions like the Suzuki-Miyaura cross-coupling. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex organic molecules. Its specific structure makes it indispensable for constructing challenging molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for oncology, CNS, and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for constructing biaryl and other complex carbon-carbon bonds under mild conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology & Proteomics: Utilized as a tool compound or linker in the development of chemical probes and bioconjugates.
• Academic & Contract Research: Essential for methodological development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	n-(4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropanecarboxamide
CAS No.	882679-35-8
Molecular Formula	C₁₇H₂₄BNO₃
Molecular Weight	301.19 g/mol
Synonyms	N-[4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxamide; Cyclopropanecarboxamide, N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 882679-35-8; 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl Cyclopropanecarboxamide; 3-Cyclopropanecarboxamido-4-methylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-(4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.