Description

3-Amino-2-Methylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling, storage, and complex multi-step synthesis. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing new active ingredients through Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating biaryl structures common in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl couplings.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs or conductive films.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-Amino-2-Methylphenylboronic Acid, Pinacol Ester
CAS No.	882678-96-8
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	2-Methyl-3-aminophenylboronic Acid Pinacol Ester; (3-Amino-2-methylphenyl)boronic Acid Pinacol Ester; 2-Methyl-3-aminobenzeneboronic Acid Pinacol Ester; 3-Amino-o-tolylboronic Acid Pinacol Ester; Pinacol (3-Amino-2-methylphenyl)boronate; B-(3-Amino-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.