Description

(Z)-Methyl 3-Amino-4-(2,4,5-Trifluorophenyl)But-2-Enoate is a high-purity fluorinated organic intermediate with significant synthetic utility. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical and agrochemical sectors seeking to introduce specific fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the trifluorophenyl group enhances biological activity and stability.
• Chemical Research: Serves as a valuable precursor for academic and industrial research into new fluorinated compounds and asymmetric synthesis methodologies.
• Material Science: Potential building block for specialty polymers and advanced materials requiring specific fluorine-based properties.

Basic Information

Product Name	(Z)-Methyl 3-Amino-4-(2,4,5-Trifluorophenyl)But-2-Enoate
CAS No.	881995-70-6
Molecular Formula	C11H11F3NO2
Molecular Weight	246.21 g/mol
Synonyms	Methyl (Z)-3-amino-4-(2,4,5-trifluorophenyl)but-2-enoate; (Z)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)-2-butenoate; Methyl 3-amino-4-(2,4,5-trifluorophenyl)-2-butenoate (Z)-; (Z)-3-Amino-4-(2,4,5-trifluorophenyl)-2-butenoic acid methyl ester; 881995-70-6; But-2-enoic acid, 3-amino-4-(2,4,5-trifluorophenyl)-, methyl ester, (Z)-
EINECS	Contact for details

Quality Control

Our (Z)-Methyl 3-Amino-4-(2,4,5-Trifluorophenyl)But-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Z-Isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.