Description

2-(4-Hexylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester, valued for its stability and reactivity in advanced synthetic chemistry. This compound is essential for facilitating key carbon-carbon bond-forming reactions, enabling the efficient synthesis of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for palladium-catalyzed coupling with aryl/vinyl halides to form biaryl and styrene derivatives, a cornerstone of modern drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs) and complex bioactive molecules.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Advanced Materials Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Biology & Medicinal Chemistry: Utilized in the synthesis of molecular probes, enzyme inhibitors, and candidate compounds for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring precise functionalization of aromatic systems.

Basic Information

Product Name	2-(4-Hexylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	881838-90-0
Molecular Formula	C18H29BO2
Molecular Weight	288.23 g/mol
Synonyms	4-Hexylbenzeneboronic acid pinacol ester; (4-Hexylphenyl)boronic acid pinacol ester; 2-(4-Hexylphenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 4-Hexylphenylboronic acid pinacol ester; Pinacol (4-hexylphenyl)boronate; 4-n-Hexylphenylboronic acid pinacol ester; B-(4-Hexylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 2-(4-Hexylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.