Description

2-Fluoro-5-Nitrobenzenesulfonamide is a specialized aromatic sulfonamide derivative, distinguished by its strategically positioned fluorine and nitro substituents. This compound serves as a critical synthetic intermediate and building block in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the sulfonamide and nitro groups.
• Material Science: Serves as a precursor for functional polymers, dyes, and advanced organic electronic materials due to its electron-withdrawing properties.
• Chemical Biology Probe: Utilized in the design of activity-based probes and affinity labels for studying biological pathways and protein function.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Ligand Synthesis: Intermediate for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-5-Nitrobenzenesulfonamide
CAS No.	881823-44-5
Molecular Formula	C6H5FN2O4S
Molecular Weight	220.18 g/mol
Synonyms	2-Fluoro-5-nitrobenzenesulfonamide; Benzenesulfonamide, 2-fluoro-5-nitro-; 5-Nitro-2-fluorobenzenesulfonamide; 2-Fluoro-5-nitrobenzene-1-sulfonamide; 881823-44-5; 2-Fluoro-5-nitrobenzenesulphonamide; 2-Fluoro-5-nitro-phenylsulfonamide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrobenzenesulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.