Description

5-Phenyl-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrole-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system and oncology applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Organic Synthesis Building Block: Serves as a versatile aldehyde component in condensation and multi-step synthesis for complex heterocycles.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up development.
• Academic Research: Utilized in university laboratories for pioneering research in synthetic methodology and new chemical entity discovery.

Basic Information

Product Name	5-Phenyl-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrole-3-Carbaldehyde
CAS No.	881676-90-0
Molecular Formula	C16H12N2O3S
Molecular Weight	312.35 g/mol
Synonyms	1H-Pyrrole-3-carboxaldehyde, 5-phenyl-1-(3-pyridinylsulfonyl)-; 5-Phenyl-1-(3-pyridylsulfonyl)pyrrole-3-carbaldehyde; 1-(Pyridin-3-ylsulfonyl)-5-phenyl-1H-pyrrole-3-carbaldehyde; 3-Formyl-5-phenyl-1-(pyridin-3-ylsulfonyl)pyrrole; 881676-90-0; 5-Phenyl-1-(3-pyridinesulfonyl)-1H-pyrrole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Phenyl-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-guided processes guarantees a reliable supply of this high-value intermediate for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.