Description

1,2-Dibromo-3-Fluoro-4-Iodo-Benzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of bromine, fluorine, and iodine atoms on a single aromatic ring makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly for introducing halogen atoms for metabolic stability or binding affinity.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the specific halogen pattern can influence biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for sequential Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the differential reactivity of its bromo and iodo substituents.
• Fluorine Chemistry Building Block: The presence of fluorine makes it valuable for research in fluorinated compounds, which are important in medicinal chemistry and advanced materials.
• Chemical Library Development: Used in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	1,2-Dibromo-3-Fluoro-4-Iodo-Benzene
CAS No.	881667-35-2
Molecular Formula	C6H2Br2FI
Molecular Weight	403.79 g/mol
Synonyms	4-Iodo-1,2-dibromo-3-fluorobenzene; 3-Fluoro-1,2-dibromo-4-iodobenzene; Benzene, 1,2-dibromo-3-fluoro-4-iodo-; 1,2-Dibromo-3-fluoro-4-iodobenzene
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3-Fluoro-4-Iodo-Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC/NMR, residual solvent levels, and other critical parameters are provided with every shipment. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in the original packaging or an amber vial until use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.