Description

2-Formylthiophene-4-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic acid derivative. This compound is essential for modern synthetic chemistry, enabling precise carbon-carbon bond formation via cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel thiophene-containing molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing the thiophene heterocycle.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate functionalized thiophene scaffolds.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up production for clients.

Basic Information

Product Name	2-Formylthiophene-4-Boronic Acid Pinacol Ester
CAS No.	881381-12-0
Molecular Formula	C13H17BO3S
Molecular Weight	264.15 g/mol
Synonyms	4-Formylthiophene-2-boronic acid pinacol ester; (4-Formylthiophen-2-yl)boronic acid pinacol ester; 2-Formyl-4-thienylboronic acid pinacol ester; 2-Thiophenecarboxaldehyde, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carbaldehyde; 881381-12-0; Pinacol 2-Formylthiophene-4-boronate
EINECS	Contact for details

Quality Control

Our 2-Formylthiophene-4-Boronic Acid Pinacol Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.