Description

7-Chloro-6-Fluoro-2,3-Dihydro-1H-Inden-1-One is a high-value, halogenated indanone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring both chloro and fluoro substituents, is engineered to impart specific electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is utilized to construct complex heterocyclic systems and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Serves as a starting material for the synthesis of specialized organic ligands and functionalized polymers with tailored properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the exploration of new chemical spaces.
• Fluorinated Compound Library: A valuable reagent for creating libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	7-Chloro-6-Fluoro-2,3-Dihydro-1H-Inden-1-One
CAS No.	881190-95-0
Molecular Formula	C9H6ClFO
Molecular Weight	184.60 g/mol
Synonyms	7-Chloro-6-fluoroindan-1-one; 1H-Inden-1-one, 7-chloro-6-fluoro-2,3-dihydro-; 6-Fluoro-7-chloro-2,3-dihydro-1H-inden-1-one; 7-Chloro-6-fluoro-2,3-dihydroinden-1-one; 7-Chloro-6-fluoro-1-indanone; 881190-95-0; FC-881190-95-0
EINECS	Contact for details

Quality Control

Our production of 7-Chloro-6-Fluoro-2,3-Dihydro-1H-Inden-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.