Description

7-Chloro-4-Fluoro-1-Indanone is a high-purity fluorinated and chlorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. This compound is valued for its unique halogenated aromatic structure, which is essential for introducing specific steric and electronic properties into target molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and chlorine atoms enhance biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or precursor for specialty polymers and organic electronic materials due to its rigid, halogenated aromatic core.
• Chemical Synthesis: Serves as a versatile scaffold in organic synthesis for constructing fused ring systems and functionalized indane derivatives.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	7-Chloro-4-Fluoro-1-Indanone
CAS No.	881190-28-9
Molecular Formula	C9H6ClFO
Molecular Weight	184.59 g/mol
Synonyms	7-Chloro-4-fluoroindan-1-one; 4-Fluoro-7-chloro-1-indanone; 1-Indanone, 7-chloro-4-fluoro-; 881190-28-9; 7-Chloro-4-fluoro-2,3-dihydro-1H-inden-1-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Fluoro-1-Indanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.