Description

5-Amino-2-([1,1'-Biphenyl]-2-Ylcarbonyl)Pentanoic Acid is a high-purity, non-natural amino acid derivative featuring a biphenyl carbonyl moiety. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Peptidomimetics Research: Used to incorporate constrained, non-proteinogenic amino acid structures into peptide analogs to enhance stability and bioavailability.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design of enzyme inhibitors.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	5-Amino-2-([1,1'-Biphenyl]-2-Ylcarbonyl)Pentanoic Acid
CAS No.	881040-80-8
Molecular Formula	C18H19NO3
Molecular Weight	297.35 g/mol
Synonyms	5-Amino-2-(2-phenylbenzoyl)pentanoic acid; 2-([1,1'-Biphenyl]-2-carbonyl)-5-aminopentanoic acid; 5-Amino-2-(biphenyl-2-carbonyl)pentanoic acid; Biphenyl carbonyl amino acid derivative; (S)-5-Amino-2-([1,1'-biphenyl]-2-ylcarbonyl)pentanoic acid (if stereospecific); L-Ornithine derivative, Biphenyl-2-carbonyl-; CAS 881040-80-8
EINECS	Contact for details

Quality Control

Our 5-Amino-2-([1,1'-Biphenyl]-2-Ylcarbonyl)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity (where applicable), and impurity profiles is provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.