Description

4,4,5,5-Tetramethyl-2-(2-(Methylsulfonyl)Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique combination of a boronate ester group and a methylsulfonyl substituent, which provides enhanced stability and reactivity for challenging cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of chemical probes and bioconjugation strategies.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel boron-containing ligands and catalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-(Methylsulfonyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	879648-22-3
Molecular Formula	C13H19BO4S
Molecular Weight	282.16 g/mol
Synonyms	2-(2-Methylsulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(Methylsulfonyl)phenyl)boronic acid pinacol ester; 2-(Methylsulfonyl)phenylboronic acid pinacol ester; 2-(2-Methanesulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(2-Methylsulfonylphenyl)boronic acid pinacol ester; 879648-22-3; (2-Methanesulphonylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-(Methylsulfonyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and consistency, from early-stage R&D to scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.