Description

Cyclopropanesulfonamide,n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester functional group. This compound matters as a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates targeting various diseases, including oncology and central nervous system disorders.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of novel APIs.
• Chemical Biology Probes: Can be utilized to create labeled compounds for studying biological pathways and target engagement.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	Cyclopropanesulfonamide,n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	879487-14-6
Molecular Formula	C15H22BNO4S
Molecular Weight	323.22 g/mol
Synonyms	N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanesulfonamide; 4-(N-Cyclopropylsulfamoyl)phenylboronic acid pinacol ester; Cyclopropanesulfonamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 879487-14-6; 4-(Cyclopropylsulfamoyl)phenylboronic acid pinacol ester; 2-[4-(Cyclopropylsulfamoyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Cyclopropanesulfonamide,n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.