Description

5-Iodo-Pyridine-3-Carbaldehyde is a versatile halogenated pyridine derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the iodine and aldehyde functional groups, which enable selective cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds in drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science.
• Organic Synthesis Research: Employed in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive iodine substituent.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Material Science Precursor: A starting material for synthesizing functionalized organic molecules used in electronic materials and OLED research.

Basic Information

Product Name	5-Iodo-Pyridine-3-Carbaldehyde
CAS No.	879326-76-8
Molecular Formula	C6H4INO
Molecular Weight	248.01 g/mol
Synonyms	3-Formyl-5-iodopyridine; 5-Iodonicotinaldehyde; 5-Iodopyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 5-iodo-; 5-Iodo-3-pyridinecarbaldehyde; 5-Iodo-3-formylpyridine; 5-Iodonicotinic aldehyde; 879326-76-8
EINECS	Contact for details

Quality Control

Our 5-Iodo-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.