Description

2-Phenylpyridine-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to create novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or heterobiaryl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic electronic materials.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds between aryl or heteroaryl groups.
• Chemical Synthesis: A versatile building block for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Ligand Synthesis: Can be utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Phenylpyridine-4-Boronic Acid Pinacol Ester
CAS No.	879291-26-6
Molecular Formula	C₁₇H₂₀BNO₂
Molecular Weight	281.16 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylpyridine; 2-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Phenylpyridine-4-boronic acid pinacol ester; 2-Phenyl-4-pyridineboronic acid pinacol ester; 4-(2-Phenylpyridin-4-yl)boronic acid pinacol ester; Pinacol 2-phenylpyridin-4-ylboronate
EINECS	Contact for details

Quality Control

Our 2-Phenylpyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.