Description

2-Chloro-1-(2-Methyl-2,3-Dihydro-Benzofuran-5-Yl)-Ethanone is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its benzofuran core structure.
• Material Science Research: Serves as a building block for developing specialty polymers and organic electronic materials.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in manufacturing.

Basic Information

Product Name	2-Chloro-1-(2-Methyl-2,3-Dihydro-Benzofuran-5-Yl)-Ethanone
CAS No.	878441-20-4
Molecular Formula	C11H11ClO2
Molecular Weight	210.66 g/mol
Synonyms	5-Acetyl-2-methyl-2,3-dihydrobenzofuran-2-carbonyl chloride (common misnomer); 2-Chloro-1-(2-methyl-2,3-dihydrobenzofuran-5-yl)ethan-1-one; 5-(2-Chloroacetyl)-2-methyl-2,3-dihydrobenzofuran; 2-Methyl-5-(2-chloroacetyl)-2,3-dihydrobenzofuran; 878441-20-4; Dihydrobenzofuran chloroethanone derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2-Methyl-2,3-Dihydro-Benzofuran-5-Yl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.