Description

4-((N,N-Dimethylamino)Methyl)Phenylboronic Acid Pinacol Ester Hydrochloride is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining the stability of a pinacol-protected boronate ester with the reactivity of a tertiary amine hydrochloride salt, making it an advanced intermediate for complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable organoboron reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific aryl-amine architectures.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers where precise molecular control is required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-((N,N-Dimethylamino)Methyl)Phenylboronic Acid Pinacol Ester Hydrochloride
CAS No.	878197-87-6
Molecular Formula	C16H27BClNO2
Molecular Weight	311.65 g/mol
Synonyms	[4-(Dimethylaminomethyl)phenyl]boronic acid pinacol ester hydrochloride; 4-(Dimethylaminomethyl)benzeneboronic acid pinacol ester hydrochloride; (4-((Dimethylamino)methyl)phenyl)boronic acid pinacol ester HCl; Pinacol [4-(N,N-dimethylaminomethyl)phenyl]boronate hydrochloride; N,N-Dimethyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanamine hydrochloride; B-[4-[(Dimethylamino)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane hydrochloride
EINECS	Contact for details

Quality Control

Our 4-((N,N-Dimethylamino)Methyl)Phenylboronic Acid Pinacol Ester Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.