Description

2-Cyano-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional organoboron building block, specifically a pyridine-boronic ester derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation tools for studying biological processes.
• Catalyst & Ligand Development: Utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: A vital reagent for methodological development and complex molecule construction in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Cyano-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	878194-93-5
Molecular Formula	C14H17BN2O2
Molecular Weight	256.11 g/mol
Synonyms	2-(2-Cyanopyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile; 2-Cyanopyridine-3-boronic acid pinacol ester; 3-(Pinacolatoboryl)picolinonitrile; 3-Borono-2-cyanopyridine pinacol ester; 2-Cyano-3-pyridylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.