Description

4-Ethoxy-1,1,1-Trifluorobut-3-En-2-Ol is a specialized fluorinated organic building block with the CAS number 878160-69-1. This compound is valued for its unique trifluoromethyl and alkoxy-substituted allylic alcohol structure, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated monomers or additives aimed at creating polymers with specific surface properties, chemical resistance, or optical characteristics.
• Liquid Crystal & Electronic Chemicals: Potential building block for fluorinated components in liquid crystal displays (LCDs) and organic electronic materials.
• Cross-Coupling Reactions: The alkene and alcohol functionalities make it a suitable substrate for various metal-catalyzed coupling reactions to create more complex molecular architectures.
• Asymmetric Synthesis: The chiral center allows for its use in the synthesis of enantiomerically pure compounds for high-value applications.

Basic Information

Product Name	4-Ethoxy-1,1,1-Trifluorobut-3-En-2-Ol
CAS No.	878160-69-1
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	4-Ethoxy-1,1,1-trifluoro-3-buten-2-ol; 1,1,1-Trifluoro-4-ethoxy-3-buten-2-ol; 3-Buten-2-ol, 4-ethoxy-1,1,1-trifluoro-; 4-Ethoxy-1,1,1-trifluorobut-3-en-2-ol; 878160-69-1; 4-Ethoxy-1,1,1-trifluoro-but-3-en-2-ol
EINECS	Contact for details

Quality Control

Every batch of 4-Ethoxy-1,1,1-Trifluorobut-3-En-2-Ol is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature and sensitivity to strong alkali/fluoride conditions, ensure the container is kept upright in a dry environment away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.