Description

(S)-2-Fluoropropan-1-Ol CAS NO 877822-87-2 is a chiral fluorinated alcohol building block of significant importance in advanced organic synthesis. Its value lies in the introduction of a fluorine atom and a chiral center, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, where the fluorine atom enhances lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving their dielectric anisotropy and performance.
• Asymmetric Catalysis & Ligand Design: Employed in the development of chiral catalysts and ligands for enantioselective synthesis processes.
• Advanced Polymer Modification: Acts as a monomer or modifier for introducing fluorine into specialty polymers to alter surface properties and chemical resistance.
• Prosthetic Group & Bio-conjugation: Useful in medicinal chemistry for creating fluorinated probes and linkers in antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Product Name	(S)-2-Fluoropropan-1-Ol
CAS No.	877822-87-2
Molecular Formula	C3H7FO
Molecular Weight	78.09 g/mol
Synonyms	(S)-2-Fluoropropan-1-ol; (S)-2-Fluoro-1-propanol; (S)-1-Fluoro-2-propanol; (S)-2-Fluoropropyl alcohol; (S)-α-Fluoropropanol; (S)-(-)-2-Fluoropropan-1-ol; (S)-2-Fluoro-propan-1-ol; (S)-2-Fluoropropanol
EINECS	Contact for details

Quality Control

Our (S)-2-Fluoropropan-1-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.