Description

(S)-(-)-2-Methyl-1-Butanol CAS NO 1565-80-6 is a high-purity chiral alcohol, specifically the (S)-enantiomer of 2-methyl-1-butanol. This compound is a critical chiral building block and resolving agent in the synthesis of fine chemicals and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, agrochemical, and specialty fragrance industries where stereochemical purity directly impacts product efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the production of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions.
• Agrochemical Synthesis: Employed in the manufacture of chiral pesticides and herbicides for enhanced biological activity.
• Flavor and Fragrance Ingredient: Serves as a precursor for specific, high-value aroma compounds.
• Chemical Research: A valuable standard and reagent in academic and industrial R&D for method development and catalysis studies.
• Electronic Chemicals: Potential use as a high-purity solvent or additive in advanced material processing.

Basic Information

Product Name	(S)-(-)-2-Methyl-1-Butanol
CAS No.	1565-80-6
Molecular Formula	C5H12O
Molecular Weight	88.15 g/mol
Synonyms	(S)-(-)-2-Methylbutan-1-ol; (S)-2-Methyl-1-butanol; L-2-Methyl-1-butanol; (S)-(-)-Active Amyl Alcohol; (2S)-2-Methyl-1-butanol; (S)-(-)-Butanol, 2-methyl-; (S)-2-Methylbutyl alcohol
EINECS	216-369-5

Quality Control

Our (S)-(-)-2-Methyl-1-Butanol is produced under strict quality management systems. Each batch is analyzed to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (ee) (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]	-5.7° to -6.0° (c=neat)
Refractive Index (n20D)	1.409 - 1.413
Density (g/mL, 20°C)	0.815 - 0.825
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.