Description

[S,(+)]-2,3-Dimethyl-1-Butanol CAS NO 15071-36-0 is a high-purity, chiral secondary alcohol characterized by its specific (S)-(+)-enantiomeric configuration. This stereochemical purity makes it a valuable chiral building block and resolving agent in asymmetric synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a key starting material or auxiliary for producing enantiomerically pure drugs, including potential antivirals, anti-inflammatories, and central nervous system (CNS) agents.
• Asymmetric Catalyst and Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysts, which are critical for enantioselective hydrogenation, oxidation, and carbon-carbon bond-forming reactions.
• Flavor and Fragrance Ingredient: Employed in the synthesis of chiral aroma chemicals, where its specific stereochemistry can influence the scent profile and quality.
• Agrochemical Research: Acts as a chiral synthon in the development of enantiomerically pure herbicides, pesticides, and plant growth regulators with improved efficacy and environmental profiles.
• Material Science: Utilized in the synthesis of chiral monomers for advanced polymers, liquid crystals, and other functional materials with specific optical properties.
• Analytical Standard: Provides a high-purity reference standard for chromatographic analysis (e.g., GC, HPLC) and optical rotation calibration in quality control laboratories.

Basic Information

Product Name	[S,(+)]-2,3-Dimethyl-1-Butanol
CAS No.	15071-36-0
Molecular Formula	C6H14O
Molecular Weight	102.17 g/mol
Synonyms	(S)-(+)-2,3-Dimethyl-1-butanol; (S)-2,3-Dimethylbutan-1-ol; (+)-2,3-Dimethyl-1-butanol; (S)-1-Butanol, 2,3-dimethyl-; L-2,3-Dimethyl-1-butanol; (2S)-2,3-Dimethylbutan-1-ol; (S)-2,3-Dimethylbutyl alcohol
EINECS	239-142-8

Quality Control

Our [S,(+)]-2,3-Dimethyl-1-Butanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, specific optical rotation measurement, and identity confirmation by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with detailed specifications for enantiomeric excess (ee), chemical purity, and physical properties to ensure it meets the stringent requirements of research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, acids, and heat sources. The container should be kept tightly sealed when not in use to minimize moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% ee
Specific Optical Rotation [α]20/D	+10.0° to +12.0° (c=1 in ethanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.