Description

6-Trifluoromethyl-1H-Indazole-3-Carboxylic Acid Methyl Ester CAS NO 877773-17-6 is a high-value fluorinated indazole derivative, serving as a critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. Its molecular structure, featuring a trifluoromethyl group and an ester moiety, makes it indispensable for medicinal chemistry research and the development of novel active ingredients. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its indazole core and fluorine substitution.
• Agrochemical Development: Building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Potential monomer or additive for specialty polymers and advanced materials requiring fluorinated components.
• Chemical Synthesis: Serves as a starting material for further functionalization, including hydrolysis to the corresponding acid or amide formation.

Basic Information

Product Name	6-Trifluoromethyl-1H-Indazole-3-Carboxylic Acid Methyl Ester
CAS No.	877773-17-6
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	Methyl 6-(trifluoromethyl)-1H-indazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 6-(trifluoromethyl)-, methyl ester; 6-Trifluoromethylindazole-3-carboxylic acid methyl ester; 6-(Trifluoromethyl)-1H-indazole-3-carboxylic acid methyl ester; Methyl 6-(trifluoromethyl)-1H-indazole-3-carboxylate; 877773-17-6; 6-CF3-1H-Indazole-3-COOCH3
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-1H-Indazole-3-Carboxylic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.