Description

4-Amino-2-Chlorophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific chlorinated aniline derivatives.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and molecular tags for studying biological processes.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized phenylboronate esters.

Basic Information

Product Name	4-Amino-2-Chlorophenylboronic Acid, Pinacol Ester
CAS No.	877160-63-9
Molecular Formula	C12H17BClNO2
Molecular Weight	253.53 g/mol
Synonyms	2-Chloro-4-aminophenylboronic acid pinacol ester; Pinacol (4-Amino-2-chlorophenyl)boronate; (4-Amino-2-chlorophenyl)boronic acid pinacol ester; 4-Amino-2-chlorobenzeneboronic acid pinacol ester; B-(4-Amino-2-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 877160-63-9; 2-Chloro-4-aminophenyl-Bpin
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chlorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.