Description

Methyl 3-(Benzyloxy)-4-Iodobenzoate is a high-purity, synthetically valuable aromatic ester and halogenated building block. This compound is specifically engineered to serve as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in programs targeting central nervous system (CNS) disorders or anti-inflammatory agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to the versatility of the iodine and benzyloxy functional groups for further cross-coupling and derivatization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Can be utilized in the development of organic electronic materials and liquid crystals, where its aromatic core and substituents modify electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	Methyl 3-(Benzyloxy)-4-Iodobenzoate
CAS No.	877064-77-2
Molecular Formula	C15H13IO3
Molecular Weight	368.17 g/mol
Synonyms	Benzoic acid, 3-(benzyloxy)-4-iodo-, methyl ester; Methyl 3-benzyloxy-4-iodobenzoate; 4-Iodo-3-(phenylmethoxy)benzoic acid methyl ester; 3-Benzyloxy-4-iodobenzoic acid methyl ester; Methyl 4-iodo-3-(phenylmethoxy)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-(Benzyloxy)-4-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC/MS for identity and impurity profiling. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.