Description

tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is a high-value, protected boronic ester derivative of a fused pyrrolopyridine heterocycle. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: For the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Synthesis: As a building block for creating new crop protection agents and herbicides with specific biological activity.
• Material Science Research: In the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Medicinal Chemistry: For the synthesis of molecular probes and tool compounds used in target identification and validation.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate
CAS No.	877060-60-1
Molecular Formula	C18H25BN2O4
Molecular Weight	344.22 g/mol
Synonyms	1-Boc-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-c]pyridine; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester; 3-Boronic acid, 1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester, pinacol ester; 877060-60-1; 1-Boc-3-(pinacol boronate)-1H-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.