Description

2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline is a high-value, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its crucial role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal boron-containing reagent for constructing biaryl and heterobiaryl systems prevalent in drug discovery.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex quinoline-based structures.
• Material Science & OLED Development: Employed in the creation of organic light-emitting diode (OLED) materials and other advanced organic electronic components.
• Ligand Synthesis: Acts as a precursor for the development of novel catalysts and chiral ligands used in asymmetric synthesis.
• Chemical Research & Development: A versatile tool for academic and industrial research in synthetic methodology development and library synthesis.

Basic Information

Product Name	2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline
CAS No.	876922-75-7
Molecular Formula	C₁₆H₂₀BNO₂
Molecular Weight	269.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylquinoline; 2-Methylquinolin-5-ylboronic acid pinacol ester; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; Quinoline, 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Methyl-5-quinolineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.