Description

1,5-Dibromo-3-Chloro-2-Ethoxybenzene is a halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its value lies in its versatile reactivity, where the strategically positioned bromine and chlorine atoms serve as excellent handles for selective cross-coupling and functional group transformations. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and specialty chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring complex, multi-substituted benzene cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogen atoms for further derivatization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic or optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromine substituents.
• Ligand and Catalyst Development: Utilized in the preparation of sophisticated ligands for metal catalysis and organocatalysts.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1,5-Dibromo-3-Chloro-2-Ethoxybenzene
CAS No.	876486-37-2
Molecular Formula	C8H7Br2ClO
Molecular Weight	338.40 g/mol
Synonyms	3-Chloro-1,5-dibromo-2-ethoxybenzene; 2-Ethoxy-1,5-dibromo-3-chlorobenzene; Benzene, 1,5-dibromo-3-chloro-2-ethoxy-; 1,5-Dibromo-3-chloro-2-ethoxybenzene; 876486-37-2
EINECS	Contact for details

Quality Control

Our 1,5-Dibromo-3-Chloro-2-Ethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.