Description

1-(4-Fluorobenzyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid is a high-purity pyrrole derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated and pyrrole motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorobenzyl and pyrrole structures can contribute to biological activity.
• Material Science Research: Serves as a precursor for functional organic materials, including organic semiconductors and ligands for catalytic systems.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	1-(4-Fluorobenzyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid
CAS No.	876294-75-6
Molecular Formula	C14H14FNO2
Molecular Weight	247.27 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid; 3-Carboxy-1-(4-fluorobenzyl)-2,5-dimethylpyrrole; 2,5-Dimethyl-1-(4-fluorobenzyl)pyrrole-3-carboxylic acid; 1H-Pyrrole-3-carboxylic acid, 1-[(4-fluorophenyl)methyl]-2,5-dimethyl-; 876294-75-6; 1-(4-Fluorobenzyl)-2,5-dimethylpyrrole-3-carboxylic acid; 1-(p-Fluorobenzyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request, ensuring full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.