Description

(E)-Ethyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or styrenyl motifs.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Intermediate for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic ester functionalities.

Basic Information

Product Name	(E)-Ethyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate
CAS No.	876169-22-1
Molecular Formula	C₁₉H₂₇BO₄
Molecular Weight	330.23 g/mol
Synonyms	Ethyl (E)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acrylate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cinnamic acid ethyl ester; (E)-Ethyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propenoate; 2-(4-[(1E)-3-Ethoxy-3-oxo-1-propen-1-yl]phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Boronophenylacrylic acid ethyl ester, pinacol ester; 4-(Ethoxycarbonylvinyl)phenylboronic acid pinacol ester; p-Vinylbenzoic acid ethyl ester boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of (E)-Ethyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acrylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide detailed Certificates of Analysis (COA) upon request, ensuring full traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.