Description

2-Bromo-5-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value aromatic nitrile building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for the synthesis of complex molecules, offering chemists strategic points for further functionalization via cross-coupling reactions and cyano group transformations. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-withdrawing properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects in fine chemical and contract research organizations (CROs).

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Phenylacetonitrile
CAS No.	875664-34-9
Molecular Formula	C9H5BrF3N
Molecular Weight	264.04 g/mol
Synonyms	2-Bromo-α-(trifluoromethyl)benzeneacetonitrile; (2-Bromo-5-(trifluoromethyl)phenyl)acetonitrile; α-Bromo-α-(trifluoromethyl)phenylacetonitrile (related isomer); 2-Bromo-5-trifluoromethylbenzyl cyanide; 875664-34-9; Benzeneacetonitrile, 2-bromo-α-(trifluoromethyl)-; 2-Br-5-CF3-Phenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.