Description

3-[2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Ethyl]Benzaldehyde is a high-value, protected aldehyde intermediate featuring a tert-butyldimethylsilyl (TBDMS) ether group. This compound is critical for synthetic chemists as it provides a versatile and stable building block for constructing complex molecules, particularly in multi-step organic synthesis where selective protection and deprotection are required. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development and production of novel pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a protected aldehyde precursor for nucleophilic addition reactions, Grignard reactions, and reductive amination.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Academic & R&D Laboratories: Essential for methodological development and exploratory chemistry in university and industrial research settings.
• Peptide & Natural Product Synthesis: Facilitates the controlled introduction of aldehyde functionalities in complex natural product and peptide analog synthesis.

Basic Information

Product Name	3-[2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Ethyl]Benzaldehyde
CAS No.	874899-89-5
Molecular Formula	C₁₅H₂₄O₂Si
Molecular Weight	264.44 g/mol
Synonyms	3-(2-((tert-Butyldimethylsilyl)oxy)ethyl)benzaldehyde; 3-[2-(tert-Butyldimethylsiloxy)ethyl]benzaldehyde; Benzaldehyde, 3-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-; TBDMS-protected 3-(2-Hydroxyethyl)benzaldehyde; 3-(2-Hydroxyethyl)benzaldehyde TBDMS ether; 3-Formylphenethyloxy-tert-butyldimethylsilane; (3-Formylphenethoxy)(tert-butyl)dimethylsilane
EINECS	Contact for details

Quality Control

Our 3-[2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Ethyl]Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.