Description

4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carbaldehyde is a high-value, multifunctional heterocyclic building block characterized by its phenyl and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties are leveraged. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated thiophene core.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of fluorescent probes and molecular tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carbaldehyde
CAS No.	874832-11-8
Molecular Formula	C12H7F3OS
Molecular Weight	256.24 g/mol
Synonyms	5-(Trifluoromethyl)-4-phenylthiophene-2-carboxaldehyde; 4-Phenyl-5-(trifluoromethyl)-2-thiophenecarboxaldehyde; 2-Formyl-4-phenyl-5-(trifluoromethyl)thiophene; 4-Phenyl-5-trifluoromethylthiophene-2-carbaldehyde; 874832-11-8; 4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Phenyl-5-(Trifluoromethyl)Thiophene-2-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.