Description

Ethyl-3-Chloro-4-Iodobenzoate is a high-purity halogenated benzoate ester, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it an essential intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Serves as a precursor for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced organic electronic materials, where the halogen atoms facilitate fine-tuning of molecular polarity and mesogenic properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl and conjugated systems.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific halogenated side chains.

Basic Information

Product Name	Ethyl-3-Chloro-4-Iodobenzoate
CAS No.	874831-02-4
Molecular Formula	C9H8ClIO2
Molecular Weight	310.52 g/mol
Synonyms	Ethyl 3-Chloro-4-iodobenzoate; Benzoic acid, 3-chloro-4-iodo-, ethyl ester; 3-Chloro-4-iodobenzoic acid ethyl ester; Ethyl 4-Iodo-3-chlorobenzoate; 874831-02-4
EINECS	Contact for details

Quality Control

Every batch of Ethyl-3-Chloro-4-Iodobenzoate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity (by IR, NMR), and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.