Description

[5-Nitro-2-(Trifluoromethoxy)Phenyl]Methanol is a high-value fluorinated aromatic building block characterized by its nitro and trifluoromethoxy substituents. This compound matters as a versatile intermediate for synthesizing advanced molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the research and production of fluorinated components for advanced liquid crystal displays (LCDs).
• Organic Electronics: Intermediate for creating electron-deficient aromatic units used in organic semiconductors and photovoltaic materials.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	[5-Nitro-2-(Trifluoromethoxy)Phenyl]Methanol
CAS No.	874821-51-9
Molecular Formula	C8H6F3NO4
Molecular Weight	237.14 g/mol
Synonyms	(5-Nitro-2-(trifluoromethoxy)phenyl)methanol; 1-(Hydroxymethyl)-2-(trifluoromethoxy)-5-nitrobenzene; 2-(Trifluoromethoxy)-5-nitrobenzyl alcohol; α-Hydroxymethyl-2-trifluoromethoxy-5-nitrobenzene; 5-Nitro-2-trifluoromethoxybenzyl Alcohol; [5-Nitro-2-(trifluoromethoxy)phenyl]carbinol
EINECS	Contact for details

Quality Control

Our [5-Nitro-2-(Trifluoromethoxy)Phenyl]Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.