Description

5-Oxo-1-[4-(Trifluoromethoxy)Phenyl]Pyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine-3-carboxylic acid core and trifluoromethoxy phenyl substituent. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the pyrrolidone and trifluoromethoxy motifs.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for medicinal chemistry, enabling the creation of diverse compound libraries for high-throughput screening.
• Active Pharmaceutical Ingredient (API) Development: Incorporated into the final structure of APIs under investigation, contributing to desired pharmacokinetic properties.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences sector.

Basic Information

Product Name	5-Oxo-1-[4-(Trifluoromethoxy)Phenyl]Pyrrolidine-3-Carboxylic Acid
CAS No.	874765-55-6
Molecular Formula	C12H10F3NO4
Molecular Weight	289.21 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-5-oxopyrrolidine-3-carboxylic acid; 5-Oxo-1-[4-(trifluoromethoxy)phenyl]-3-pyrrolidinecarboxylic acid; 3-Pyrrolidinecarboxylic acid, 5-oxo-1-[4-(trifluoromethoxy)phenyl]-; 874765-55-6; 5-Oxo-1-(4-trifluoromethoxyphenyl)pyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-[4-(Trifluoromethoxy)Phenyl]Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.