Description

Boronic Acid, B-[3-[(2-Propyn-1-Ylamino)Carbonyl]Phenyl]- is a specialized organoboron compound featuring a phenylboronic acid core functionalized with a propargylamide linker. This molecular architecture makes it a versatile and high-value building block for advanced organic synthesis, particularly in the development of targeted pharmaceuticals and novel materials. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, where it serves as a key precursor for Suzuki-Miyaura cross-coupling reactions and bioconjugation strategies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting specific biological pathways.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds for constructing complex biaryl structures common in modern agrochemicals and pharmaceuticals.
• Bioconjugation and Probe Development: The boronic acid and alkyne functional groups allow for selective conjugation to biomolecules (like sugars or proteins) for diagnostic probes and targeted drug delivery systems.
• Material Science Research: Used in the development of advanced polymeric materials, sensors, and metal-organic frameworks (MOFs) due to its ability to form reversible covalent bonds.
• Chemical Biology Tool: Facilitates the study of biological processes through its use in activity-based protein profiling and the development of covalent inhibitors.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators with improved efficacy.

Basic Information

Product Name	Boronic Acid, B-[3-[(2-Propyn-1-Ylamino)Carbonyl]Phenyl]-
CAS No.	874459-94-6
Molecular Formula	C11H10BNO3
Molecular Weight	215.02 g/mol
Synonyms	3-(Prop-2-yn-1-ylcarbamoyl)phenylboronic acid; 3-[(Prop-2-yn-1-ylamino)carbonyl]benzeneboronic acid; N-Propargyl-3-carbamoylphenylboronic acid; B-[3-[(2-Propyn-1-ylamino)carbonyl]phenyl]boronic acid; Propargylamide Phenylboronic Acid; 3-Carbamoylphenylboronic Acid Propargylamide; (3-((Prop-2-yn-1-ylcarbamoyl))phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[3-[(2-Propyn-1-Ylamino)Carbonyl]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR and NMR), and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.