Description

n-Propargyl 4-Boronobenzamide is a specialized boronic acid derivative that serves as a versatile building block in modern synthetic chemistry. Its unique structure, combining a propargyl group with a boronic acid moiety, makes it a valuable reagent for cross-coupling reactions and bioconjugation strategies. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Bioconjugation Reagent: Used in click chemistry applications, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), for labeling biomolecules.
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents requiring specific boron-containing motifs.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of boron-doped polymers and advanced organic frameworks.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and protein interactions.
• Academic & Industrial R&D: Serves as a fundamental research chemical for exploring new catalytic methodologies and reaction pathways.

Basic Information

Product Name	n-Propargyl 4-Boronobenzamide
CAS No.	874459-89-9
Molecular Formula	C10H10BNO2
Molecular Weight	187.01 g/mol
Synonyms	4-(Prop-2-yn-1-ylcarbamoyl)phenylboronic acid; 4-Boronobenzoic acid propargylamide; Propargyl 4-boronobenzamide; p-Boronobenzoylpropargylamine; 4-Carbamoylphenylboronic acid propargyl ester; B-(4-((Prop-2-yn-1-yl)carbamoyl)phenyl)boronic acid; N-Propargyl-4-boronobenzamide
EINECS	Contact for details

Quality Control

Our n-Propargyl 4-Boronobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.