Description

4-(2-Acetylaminoethyl)Phenylboronic Acid is a specialized boronic acid derivative featuring an acetylaminoethyl linker, making it a valuable building block in modern synthetic chemistry. This compound is particularly significant for its role in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring biaryl structures common in kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in constructing novel herbicide and pesticide molecules through palladium-catalyzed cross-coupling reactions.
• Material Science: Serves as a monomer or precursor in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized in the development of boronic acid-based sensors, affinity probes, and inhibitors for serine hydrolases.
• Academic & Process R&D: Employed in methodological studies and scale-up process development for catalytic cross-coupling reactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	4-(2-Acetylaminoethyl)Phenylboronic Acid
CAS No.	874459-75-3
Molecular Formula	C10H14BNO3
Molecular Weight	207.04 g/mol
Synonyms	[2-(4-Boronophenyl)ethyl]acetamide; N-[2-(4-Boronophenyl)ethyl]acetamide; 4-(2-Acetamidoethyl)benzeneboronic Acid; 4-(2-Acetylaminoethyl)benzeneboronic Acid; 2-(4-Boronophenyl)ethylacetamide; B-[4-(2-Acetamidoethyl)phenyl]boronic Acid; 874459-75-3 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4-(2-Acetylaminoethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.