Description

(n-Acrylamidophenyl)Boronic Acid Pinacol Ester is a specialized bifunctional monomer that combines a polymerizable acrylamide group with a protected boronic acid moiety. This compound matters for its unique ability to serve as a key building block in the synthesis of advanced functional polymers and materials. It is primarily needed by researchers and manufacturers in the pharmaceutical, materials science, and sensor technology industries for applications such as creating stimuli-responsive hydrogels, affinity separation media, and diagnostic platforms.

Application

• Synthesis of Boron-Containing Polymers: As a polymerizable monomer for creating hydrogels and smart materials with glucose-responsive properties.
• Pharmaceutical Intermediate: Used in the research and development of proteolysis-targeting chimeras (PROTACs) and other novel therapeutic agents.
• Affinity Chromatography Ligands: Immobilization onto solid supports to create columns for the selective separation of cis-diol containing compounds like sugars and catechols.
• Biosensor Development: Functionalization of surfaces for electrochemical or optical sensing platforms targeting biological analytes.
• Surface Modification: Crafting functional coatings on nanoparticles or other substrates for targeted drug delivery or diagnostic applications.
• Crosslinking Agent: Utilized in polymer networks where reversible binding via the boronic acid group is desired.
• Organic Synthesis Building Block: Serves as a protected boronic acid reagent in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl structures.
• Material Science Research: Exploration of novel self-healing or shape-memory polymers leveraging dynamic boronate ester bonds.

Basic Information

Product Name	(n-Acrylamidophenyl)Boronic Acid Pinacol Ester
CAS No.	874363-18-5
Molecular Formula	C17H24BNO3
Molecular Weight	301.19 g/mol
Synonyms	4-Acrylamidophenylboronic Acid Pinacol Ester; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylamide; 4-Acrylamidobenzeneboronic Acid Pinacol Ester; Acrylamidophenylboronic Acid Pinacol Ester; p-Acrylamidophenylboronic Acid Pinacol Ester; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]prop-2-enamide
EINECS	Contact for details

Quality Control

Our (n-Acrylamidophenyl)Boronic Acid Pinacol Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR and HPLC. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester moiety. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.